data A;
input title $ 1-39;
datalines;
A TALE OF TWO CITIES
GENERAL MANAGER IN ONE CITY
MANAGER IS IN ANOTHER CITY
MANAGER IS NOT IN THE CITY

run;

data work;
  set A;
WORD=FIND(title,"IS IN","IS NOT","i"); /**** "i" is to handle the case insensitive ****/
run;